Shuttle bus from the cruise port to the city center of Venice
There's no traffic allowed in the center of Venice, so it's impossible to get there by bus or car. Some cruise lines offer a shuttle bus to the People Mover station or Piazzale Roma. From there you can continue on foot or by water transport.
Sometimes cruise lines also offer a shuttle service by boat from the cruise port to Piazza San Marco. This is a fun way to go to the city center.
TIP: Unless the shuttle is free of charge, you should check the price in advance. There are several other options such as a water taxi, walk, an Alilaguna boat or a canal bus (Vaporetti).
More transportation options: